GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ephx1 | increases expression | EXP | | 6480464 | CTD | Methamphetamine results in increased expression of EPHX1 mRNA; Methamphetamine results in increased expression of EPHX1 protein | PMID:26307267 PMID:31422080 | Ephx1 | increases methylation | EXP | | 6480464 | CTD | Methamphetamine results in increased methylation of EPHX1 promoter | PMID:26307267 | Ephx1 | multiple interactions | EXP | | 6480464 | CTD | EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein] | PMID:31422080 | |
Go Back to source page | Continue to Ontology report |