GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egr1 | increases expression | ISO | EGR1 (Homo sapiens) | 6480464 | CTD | sulindac sulfide results in increased expression of EGR1 mRNA; sulindac sulfide results in increased expression of EGR1 protein | PMID:15509713 PMID:16079301 PMID:16227405 PMID:17599376 | Egr1 | multiple interactions | ISO | EGR1 (Homo sapiens) | 6480464 | CTD | EGR1 protein affects the reaction [sulindac sulfide results in increased expression of THBS1 mRNA]; EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of ATF3 mRNA]; EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of GDF15 mRNA]; ELK1 protein promotes the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]; MAPK1 protein promotes the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]; MAPK3 protein promotes the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]; U 0126 inhibits the reaction [sulindac sulfide results in increased expression of EGR1 mRNA] | PMID:15509713 PMID:16079301 PMID:16227405 PMID:17599376 | | ||||||||||||||||||||||
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