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RGD ID: 10510
Species: Mus musculus
RGD Object: Gene
Symbol: Egf
Name: epidermal growth factor
Acc ID: GO:0007173
Term: epidermal growth factor receptor signaling pathway
Definition: A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:ceb, PR:000006933
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IDA 2290270MGI (MGI:MGI:3531070, PMID:15695332), (MGI:MGI:63909, PMID:6315706)

MGI:MGI:3531070, MGI:MGI:63909, PMID:15695332, PMID:6315706
 IGIMGI:MGI:952942290270MGI (MGI:MGI:75839, PMID:7641815)

MGI:MGI:75839, PMID:7641815
 ISORGD:25422290270RGD GO_REF:0000096, MGI:MGI:4417868
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.