GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egf | decreases expression | ISO | EGF (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in decreased expression of EGF mRNA | PMID:20346928 PMID:20706672 | Egf | multiple interactions | ISO | EGF (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [EGF protein binds to EGFR protein]; epigallocatechin gallate inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to EGFR protein]]; epigallocatechin gallate inhibits the reaction [EGF protein results in increased activity of SP1 protein]; epigallocatechin gallate inhibits the reaction [EGF protein results in increased expression of FAS mRNA]; epigallocatechin gallate inhibits the reaction [EGF protein results in increased expression of FAS protein]; epigallocatechin gallate inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; epigallocatechin gallate inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] | PMID:12931129 PMID:17616711 | | ||||||||||||||||||||||
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