GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egf | affects activity | ISO | EGF (Homo sapiens) | 6480464 | CTD | Tamoxifen affects the activity of EGF protein | PMID:19395996 | Egf | increases response to substance | ISO | EGF (Homo sapiens) | 6480464 | CTD | EGF protein results in increased susceptibility to Tamoxifen | PMID:14649542 | Egf | multiple interactions | ISO | EGF (Homo sapiens) | 6480464 | CTD | [EGF protein results in increased activity of EGFR protein] which results in decreased susceptibility to Tamoxifen; EGFR mutant form inhibits the reaction [[EGF protein results in increased activity of EGFR protein] which results in decreased susceptibility to Tamoxifen]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of ARTN mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of CCND1 mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of CDC6 mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of CXCL12 mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of GFRA2 mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of MCM4 mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of MCM7 mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of MERTK mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of RET mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of SGK1 mRNA]; Tamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of TGFA mRNA]; Tamoxifen inhibits the reaction [EGF protein results in increased expression of FCMR mRNA]; Tamoxifen inhibits the reaction [EGF protein results in increased expression of GADD45A mRNA]; Tamoxifen inhibits the reaction [EGF protein results in increased expression of HBEGF mRNA]; Tamoxifen inhibits the reaction [EGF protein results in increased expression of IL20 mRNA]; Tamoxifen inhibits the reaction [EGF protein results in increased expression of RELB mRNA] | PMID:24758408 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |