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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10509
Species: Mus musculus
RGD Object: Gene
Symbol: Efnb3
Name: ephrin B3
Acc ID: CHEBI:27732
Term: caffeine
Definition: A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
Chemical ID: MESH:D002110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Caffeine co-treated with 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine] results in increased expression of EFNB3 mRNA, Caffeine inhibits the reaction [1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine results in increased expression of EFNB3 mRNA]

PMID:20230807
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