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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10474
Species: Mus musculus
RGD Object: Gene
Symbol: Dio1
Name: deiodinase, iodothyronine, type I
Acc ID: CHEBI:35430
Term: 3,3'-diiodothyronine
Definition: An iodothyronine that has formula C15H13I2NO4.
Chemical ID: MESH:C030629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dio1multiple interactionsISODIO1 (Homo sapiens)6480464CTD[DIO1 protein results in increased metabolism of Triiodothyronine, Reverse] which results in increased abundance of 3,3'-diiodothyronine; Iodoacetates inhibits the reaction [[DIO1 protein results in increased metabolism of Triiodothyronine, Reverse] which results in increased abundance of 3,3'-diiodothyronine]PMID:21565810
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