GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nqo1 | increases expression | EXP | | 6480464 | CTD | N-acetyl-4-benzoquinoneimine results in increased expression of NQO1 mRNA | PMID:18785192 | Nqo1 | increases metabolic processing | EXP | | 6480464 | CTD | NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine | PMID:19246624 | Nqo1 | multiple interactions | EXP | | 6480464 | CTD | KEAP1 protein inhibits the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine]; NFE2L2 protein affects the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine] | PMID:18785192 PMID:19246624 | Nqo1 | increases reduction | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | NQO1 protein results in increased reduction of N-acetyl-4-benzoquinoneimine | PMID:17188792 | Nqo1 | multiple interactions | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | NQO1 protein inhibits the reaction [GSTP1 protein results in increased glutathionylation of N-acetyl-4-benzoquinoneimine] | PMID:24552538 | | ||||||||||||||||||||||
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