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GENE - TERM ANNOTATION REPORT

RGD ID: 10468
Species: Mus musculus
RGD Object: Gene
Symbol: Ace
Name: angiotensin I converting enzyme
Acc ID: DOID:5844
Term: myocardial infarction
Definition: A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Myocardial_infarction "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/17951287 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ace ISOAce (Rattus norvegicus)6893480RGDassociated with Myocardial Reperfusion Injury 
AcesusceptibilityISOACE (Homo sapiens)7829785RGDassociated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human) 
AcetreatmentISOAce (Rattus norvegicus)1558664RGD  
AcetreatmentISOAce (Rattus norvegicus)9685449RGD  
Ace ISOACE (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:1328889 PMID:8131300
Ace ISOACE (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Myocardial infarction, susceptibility toPMID:10099885 PMID:10636736 PMID:10643899 PMID:10841123 PMID:11687636 PMID:11956052 PMID:12220450 PMID:12666117 PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:14657821 PMID:14872014 PMID:15110771 PMID:15277638 PMID:15381116 PMID:15531537 PMID:15534175 PMID:15635071 PMID:19221299 PMID:1976655 PMID:25741868 PMID:2847529 PMID:2849100 PMID:28492532 PMID:7593601 PMID:7729604 PMID:7783416 PMID:7854377 PMID:7909524 PMID:8131299 PMID:8131300 PMID:8136829 PMID:8170965 PMID:8208911 PMID:8298638 PMID:8314010 PMID:8541160 PMID:8644984 PMID:8675669 PMID:9120002 PMID:9236417 PMID:9259580 PMID:9699903 PMID:9737775 PMID:9916793
Ace ISOACE (Homo sapiens)1331525GAD  
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