GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp7a1 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of CYP7A1 mRNA | PMID:32156529 | Cyp7a1 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of CYP7A1 mRNA | PMID:17706920 PMID:27502578 | Cyp7a1 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP7A1 mRNA; [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of CYP7A1 mRNA; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with Dietary Fats] results in increased expression of CYP7A1 mRNA; LHB protein affects the reaction [bisphenol A results in increased expression of CYP7A1 mRNA] | PMID:17706920 PMID:23756648 PMID:28433925 PMID:30722647 | Cyp7a1 | affects expression | ISO | Cyp7a1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A affects the expression of CYP7A1 mRNA | PMID:30903817 | Cyp7a1 | decreases expression | ISO | Cyp7a1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of CYP7A1 mRNA | PMID:25181051 PMID:32145629 PMID:35192832 | Cyp7a1 | decreases expression | ISO | CYP7A1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of CYP7A1 mRNA | PMID:23146750 | |
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