An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID:
MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[1-methylanthracene co-treated with fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA; [arsenite co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA; [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CYP1B1 mRNA; [chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of CYP1B1 mRNA; [Resveratrol co-treated with Benzo(a)pyrene] results in decreased expression of CYP1B1 protein; [SOD1 protein co-treated with CAT protein] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; [SOD1 protein co-treated with CAT protein] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; AHR protein affects the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]; AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]; Benzo(a)pyrene inhibits the reaction [Dust results in increased expression of CYP1B1 protein]; Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1B1 promoter]; Benzo(a)pyrene promotes the reaction [sodium bichromate results in increased expression of CYP1B1 mRNA]; Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1B1 protein; CYP1B1 gene mutant form promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Dust inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; ellipticine inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]; Ethanol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; MAPK14 protein promotes the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]; Resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; SOD1 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; SOD1 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]
Benzo(a)pyrene analog results in increased expression of CYP1B1 mRNA; Benzo(a)pyrene analog results in increased expression of CYP1B1 protein; Benzo(a)pyrene results in increased expression of CYP1B1; Benzo(a)pyrene results in increased expression of CYP1B1 mRNA; Benzo(a)pyrene results in increased expression of CYP1B1 protein
Benzo(a)pyrene results in increased methylation of CYP1B1 3' UTR; Benzo(a)pyrene results in increased methylation of CYP1B1 exon; Benzo(a)pyrene results in increased methylation of CYP1B1 promoter
1,2,5,6-dibenzanthracene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]; 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; 1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]; [benz(a)anthracene co-treated with benzo(b)fluoranthene] promotes the reaction [chrysene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]; [Benzo(a)pyrene co-treated with Oxygen] affects the expression of CYP1B1 protein; [chrysene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; [chrysene co-treated with benz(a)anthracene] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; [chrysene co-treated with Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA; [chrysene co-treated with Benzo(a)pyrene co-treated with benz(a)anthracene] results in increased expression of CYP1B1 mRNA; [chrysene co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA; AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Benzo(a)pyrene promotes the reaction [TNF protein promotes the reaction [CDK9 protein binds to CYP1B1 promoter]]; Benzo(a)pyrene promotes the reaction [TNF protein promotes the reaction [POLR2A protein binds to CYP1B1 promoter]]; Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 mRNA]; Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 protein]; benzo(b)fluoranthene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]; chrysene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; chrysene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; dibenzo(a,l)pyrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 protein]]; EGF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; EGF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; Ethinyl Estradiol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; fluoranthene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]; Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; TNF promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; TNF promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]
2',5'-dideoxyadenosine inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 2,4,3',5'-tetramethoxystilbene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]; 3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]; 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; [Benzo(a)pyrene co-treated with Vehicle Emissions] results in decreased expression of CYP1B1 protein; [CYP1B1 protein results in increased metabolism of Benzo(a)pyrene] which results in increased expression of TP53 protein modified form; [CYP1B1 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene; [Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA; [Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 protein; [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA; AHR mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1]; AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; AR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of CYP1B1 mRNA]; Benzo(a)pyrene affects the reaction [CYP1B1 protein results in increased hydroxylation of Estradiol]; Benzo(a)pyrene promotes the reaction [Estradiol results in increased expression of CYP1B1 mRNA]; Brefeldin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Butyric Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; CAT promotes the reaction [CYP1B1 gene SNP inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene-DNA adduct]]; chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; chrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; cobaltous chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; CXCL8 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; CYP1B1 gene SNP inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene-DNA adduct]; CYP1B1 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]; CYP1B1 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP7 mRNA]; CYP1B1 protein affects the metabolism of and results in increased activity of Benzo(a)pyrene; CYP1B1 protein polymorphism affects the metabolism of and results in increased activity of Benzo(a)pyrene; CYP1B1 protein results in increased metabolism of and results in increased activity of Benzo(a)pyrene; Estradiol promotes the reaction [Benzo(a)pyrene analog results in increased expression of CYP1B1 mRNA]; Estradiol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; GUSB protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; ICI 118551 inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; IL6 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Particulate Matter inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Propranolol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; pyrene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Resveratrol inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]; Resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Suramin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; TNF promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; trichostatin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Vorinostat inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]
