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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10439
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1decreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of CYP1B1 mRNAPMID:11353140 PMID:37682722
Cyp1b1increases expressionEXP 6480464CTDsodium arsenite results in increased expression of CYP1B1 mRNAPMID:25065748
Cyp1b1affects methylationISOCYP1B1 (Homo sapiens)6480464CTDsodium arsenite affects the methylation of CYP1B1 genePMID:28589171
Cyp1b1decreases expressionISOCYP1B1 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of CYP1B1 mRNAPMID:12727804 PMID:22714537 PMID:34032870
Cyp1b1increases expressionISOCYP1B1 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of CYP1B1 mRNAPMID:29301061
Cyp1b1multiple interactionsISOCYP1B1 (Homo sapiens)6480464CTD[Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CYP1B1 mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CYP1B1 mRNA; [sodium arsenite results in increased abundance of arsenite] which results in decreased expression of CYP1B1 mRNAPMID:32076005 PMID:35747940
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