An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID:
MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[Benzo(a)pyrene co-treated with sodium bichromate] results in decreased expression of CYP1A2 mRNA; [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of Benzo(a)pyrene; [fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA; AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of CYP1A2 mRNA]; Bucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Cycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Benzo(a)pyrene]; Lipopolysaccharides inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]
[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CYP1A2 mRNA; [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA; [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of CYP1A2 mRNA; [chrysene co-treated with Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1A2 mRNA; [chrysene co-treated with Benzo(a)pyrene co-treated with benz(a)anthracene] results in increased expression of CYP1A2 mRNA; [chrysene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA; [Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; [Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; atipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]]; atipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]; atipamezole promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; atipamezole promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Benzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein; Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Guanethidine inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]; INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Oxygen inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]; Prazosin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Prazosin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Wortmannin inhibits the reaction [INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]
2-oxohexyl isothiocyanate inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]; [Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CYP1A2 mRNA; [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA; [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of Benzo(a)pyrene; [CYP1A2 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene; AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; alyssin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]; Benzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Benzo(a)pyrene promotes the reaction [Butyric Acid results in increased expression of CYP1A2 mRNA]; beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; beta-apo-8'-carotenal promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Butyric Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; chrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; cryptotanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; cryptotanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; CYP1A2 protein results in increased metabolism of and results in increased activity of Benzo(a)pyrene; dihydrotanshinone I promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; dihydrotanshinone I promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Benzo(a)pyrene]; kaempferol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Melatonin inhibits the reaction [CYP1A2 protein results in increased hydrolysis of Benzo(a)pyrene]; Quercetin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]; Quercetin inhibits the reaction [beta-apo-8'-carotenal promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]; Resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]; tanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; tanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]
