Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10356
Species: Homo sapiens
RGD Object: Gene
Symbol: CHRNA4
Name: cholinergic receptor nicotinic alpha 4 subunit
Acc ID: CHEBI:3385
Term: carbachol
Definition: An ammonium salt that has formula C6H15N2O2.Cl.
Chemical ID: MESH:D002217
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CHRNA4multiple interactionsISOChrna4 (Rattus norvegicus)2303194RGDcarbachol affects binding to Chrna4 protein; carbachol competes with [Epibatidine binds to Chrna4 protein] 
CHRNA4multiple interactionsEXP 6480464CTDCarbachol inhibits the reaction [decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Carbachol inhibits the reaction [Dihydro-beta-Erythroidine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Carbachol inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Carbachol inhibits the reaction [methyllycaconitine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Carbachol results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]PMID:14645658
CHRNA4affects bindingISOChrna4 (Rattus norvegicus)6480464CTDCarbachol binds to [CHRNA4 protein binds to CHRNB2 protein]PMID:15615518
Go Back to source page   Continue to Ontology report