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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10355
Species: Mus musculus
RGD Object: Gene
Symbol: Chrna4
Name: cholinergic receptor, nicotinic, alpha polypeptide 4
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrna4multiple interactionsISOChrna4 (Rattus norvegicus)6480464CTDCocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]PMID:10336510
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