GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cebpa | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of CEBPA mRNA; bisphenol A results in decreased expression of CEBPA protein | PMID:26146954 PMID:30133442 | Cebpa | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of CEBPA; bisphenol A results in increased expression of CEBPA mRNA; bisphenol A results in increased expression of CEBPA protein | PMID:26942597 PMID:26996129 PMID:27145005 PMID:30959087 PMID:32156529 PMID:32623698 | Cebpa | multiple interactions | EXP | | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with bisphenol A co-treated with INS protein] results in increased expression of CEBPA protein; [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA; [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of CEBPA mRNA; MAP2K3 protein inhibits the reaction [MIR21A mRNA inhibits the reaction [bisphenol A results in increased expression of CEBPA mRNA]]; MAP2K3 protein inhibits the reaction [MIR21A mRNA inhibits the reaction [bisphenol A results in increased expression of CEBPA protein]]; Mifepristone inhibits the reaction [bisphenol A results in increased expression of CEBPA mRNA]; MIR21A mRNA inhibits the reaction [bisphenol A results in increased expression of CEBPA mRNA]; MIR21A mRNA inhibits the reaction [bisphenol A results in increased expression of CEBPA protein] | PMID:26820058 PMID:26996129 PMID:27145005 PMID:27273607 PMID:30665118 | Cebpa | decreases expression | ISO | Cebpa (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of CEBPA mRNA | PMID:25181051 PMID:25748669 PMID:28657538 | Cebpa | decreases expression | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | bisphenol A analog results in decreased expression of CEBPA mRNA; bisphenol A results in decreased expression of CEBPA mRNA | PMID:32387340 | Cebpa | increases expression | ISO | Cebpa (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of CEBPA mRNA | PMID:20019905 PMID:30816183 PMID:34165232 PMID:35192832 | Cebpa | increases expression | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of CEBPA mRNA; bisphenol A results in increased expression of CEBPA protein | PMID:24418828 PMID:25143472 PMID:32175033 PMID:32623698 PMID:35622622 | Cebpa | increases methylation | ISO | Cebpa (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased methylation of CEBPA gene | PMID:28505145 | Cebpa | increases methylation | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased methylation of CEBPA gene | PMID:31601247 | Cebpa | multiple interactions | ISO | Cebpa (Rattus norvegicus) | 6480464 | CTD | lithospermate B inhibits the reaction [bisphenol A results in increased expression of CEBPA mRNA] | PMID:34165232 | Cebpa | multiple interactions | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CEBPA mRNA; [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CEBPA protein; [bisphenol A co-treated with Fulvestrant] results in increased methylation of CEBPA gene; [Vitamin D co-treated with bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] affects the expression of CEBPA mRNA; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CEBPA protein] | PMID:31601247 PMID:33836827 PMID:35622622 PMID:35736896 | | ||||||||||||||||||||||
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