GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | diallyl trisulfide results in increased activity of CASP3 protein | PMID:20055834 PMID:21574149 PMID:22595511 PMID:23754639 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | diallyl trisulfide results in increased cleavage of CASP3 protein | PMID:22578287 PMID:25205294 PMID:27566995 PMID:34995734 | Casp3 | increases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | diallyl trisulfide results in increased expression of CASP3 mRNA | PMID:21574149 | Casp3 | multiple interactions | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]] | PMID:23453443 PMID:24295472 PMID:25896937 PMID:29087013 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein] | PMID:22578287 PMID:27566995 PMID:28571773 PMID:31115753 | | ||||||||||||||||||||||
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