GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | multiple interactions | EXP | | 6480464 | CTD | bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein] | PMID:29111403 | Casp3 | decreases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | bafilomycin A1 results in decreased activity of CASP3 protein | PMID:25981168 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | bafilomycin A1 results in increased activity of CASP3 protein | PMID:28063998 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | bafilomycin A1 results in increased cleavage of CASP3 protein | PMID:26853465 PMID:32708634 | Casp3 | multiple interactions | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | [Swainsonine co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein] | PMID:24889822 PMID:28378122 PMID:33186601 PMID:34374793 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | [bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; [bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; bafilomycin A1 inhibits the reaction [tetrandrine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein]; vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of CASP3 protein] | PMID:20876807 PMID:23380477 PMID:24321340 PMID:25266202 PMID:26853465 PMID:28063998 PMID:30240709 PMID:32708634 PMID:33076330 | | ||||||||||||||||||||||
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