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GENE - TERM ANNOTATION REPORT

RGD ID: 10265
Species: Mus musculus
RGD Object: Gene
Symbol: Cacna1a
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Acc ID: GO:0005245
Term: voltage-gated calcium channel activity
Definition: Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Definition Source(s): GOC:mtg_transport, GOC:tb, ISBN:0815340729
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAFB:FBgn0001991, FB:FBgn0263111, MGI:MGI:103013, MGI:MGI:106217, MGI:MGI:109482, MGI:MGI:1859639, MGI:MGI:88294, MGI:MGI:88296, PANTHER:PTN001295314, RGD:2244, RGD:2245, RGD:2246, RGD:628852, RGD:70973, UniProtKB:O00555, UniProtKB:O60840, UniProtKB:Q01668, UniProtKB:Q13698, UniProtKB:Q13936, UniProtKB:Q15878, WB:WBGene000011872290270GO_Central (PMID:21873635)

PMID:21873635
 IDA 2290270MGI (MGI:MGI:79428, PMID:8632762)

MGI:MGI:79428, PMID:8632762
 IMP 2290270MGI (MGI:MGI:3040168, PMID:12827191)

MGI:MGI:3040168, PMID:12827191
 IMPMGI:MGI:18562092290270MGI (MGI:MGI:3619817, PMID:12151514)

MGI:MGI:3619817, PMID:12151514
 IMPMGI:MGI:1856209, MGI:MGI:18562102290270MGI (MGI:MGI:1321414, PMID:9857013)

MGI:MGI:1321414, PMID:9857013
 IMPMGI:MGI:18562102290270MGI (MGI:MGI:1261389, PMID:9614225)

MGI:MGI:1261389, PMID:9614225
 IMPMGI:MGI:21813842290270MGI (MGI:MGI:1350870, PMID:10611370)

MGI:MGI:1350870, PMID:10611370
 ISORGD:22442290270RGD GO_REF:0000096, MGI:MGI:4417868
 ISOUniProtKB:O005552290270MGI GO_REF:0000096, MGI:MGI:4834177
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.