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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10265
Species: Mus musculus
RGD Object: Gene
Symbol: Cacna1a
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7359506480464CTDValproic Acid affects the expression of CACNA1A mRNA

PMID:25979313
affects splicingISORGD:22446480464CTDValproic Acid affects the splicing of CACNA1A mRNA

PMID:29427782
increases expressionISORGD:7359506480464CTDValproic Acid results in increased expression of CACNA1A mRNA

PMID:23179753, PMID:24935251, PMID:27188386
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.