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GENE - TERM ANNOTATION REPORT

RGD ID: 10256
Species: Mus musculus
RGD Object: Gene
Symbol: C3
Name: complement component 3
Acc ID: DOID:5162
Term: arteriolosclerosis
Definition: An arteriosclerosis that is characterized by thickening of the wall of the small arteries and arterioles, caused by deposition of hyaline material in the wall or concentric smooth muscle wall hypertrophy, and results in lumen narrowing and tissue ischemia. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Arteriolosclerosis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C3 ISOC3 (Homo sapiens)7175516RGDassociated with Renal Insufficiency, Chronic; protein:increased expression:serum: 
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