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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10248
Species: Mus musculus
RGD Object: Gene
Symbol: Bsg
Name: basigin
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bsgdecreases expressionISOBSG (Homo sapiens)6480464CTDresveratrol results in decreased expression of BSG proteinPMID:17007354
Bsgmultiple interactionsISOBSG (Homo sapiens)6480464CTD2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol results in decreased expression of BSG protein]; resveratrol inhibits the reaction [BSG protein results in increased expression of and results in increased secretion of IL18 protein]; resveratrol inhibits the reaction [BSG protein results in increased expression of IL18 mRNA]; resveratrol inhibits the reaction [IL18 protein results in increased expression of BSG mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG]PMID:17007354 PMID:17055343 PMID:18647594 PMID:19561311
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