GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bdnf | decreases expression | EXP | | 6480464 | CTD | Rotenone results in decreased expression of BDNF protein | PMID:36774383 | Bdnf | multiple interactions | EXP | | 6480464 | CTD | BDNF protein affects the reaction [PITX3 protein results in decreased susceptibility to Rotenone]; oleuropein affects the reaction [Rotenone results in decreased expression of BDNF protein] | PMID:18646205 PMID:36774383 | Bdnf | decreases expression | ISO | Bdnf (Rattus norvegicus) | 6480464 | CTD | Rotenone results in decreased expression of BDNF mRNA; Rotenone results in decreased expression of BDNF protein | PMID:17442543 PMID:23189969 PMID:25446674 PMID:28238857 PMID:28389404 PMID:35104487 PMID:36706892 | Bdnf | increases expression | ISO | BDNF (Homo sapiens) | 6480464 | CTD | Rotenone results in increased expression of BDNF mRNA | PMID:29955902 | Bdnf | multiple interactions | ISO | Bdnf (Rattus norvegicus) | 6480464 | CTD | Apigenin inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]; asiaticoside inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]; echinacoside inhibits the reaction [Rotenone results in decreased expression of BDNF protein]; Haloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]; Risperidone inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]; Roflumilast inhibits the reaction [Rotenone results in decreased expression of BDNF protein]; saxagliptin inhibits the reaction [Rotenone results in decreased expression of BDNF protein]; staurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased expression of BDNF protein]] | PMID:17442543 PMID:23189969 PMID:25446674 PMID:28238857 PMID:28389404 PMID:36706892 | |
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