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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10187
Species: Mus musculus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:82315
Term: 3,3'-Dichlorobenzidine
Definition: A monochlorobenzene that has formula C12H10Cl2N2.
Chemical ID: MESH:D015101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Araffects localizationISOAR (Homo sapiens)6480464CTD3,3'-Dichlorobenzidine analog affects the localization of AR proteinPMID:28478275
Armultiple interactionsISOAR (Homo sapiens)6480464CTD3,3'-Dichlorobenzidine analog binds to and results in increased activity of AR protein; 3,3'-Dichlorobenzidine binds to and results in decreased activity of AR protein; 3,3'-Dichlorobenzidine inhibits the reaction [Metribolone results in increased activity of AR protein]PMID:15950433 PMID:18324785 PMID:28478275
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