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GENE - TERM ANNOTATION REPORT

RGD ID: 10183
Species: Mus musculus
RGD Object: Gene
Symbol: Aqp4
Name: aquaporin 4
Acc ID: DOID:4724
Term: brain edema
Definition: A brain disease that is characterized by excess accumulation of fluid in the intracellular and/or extracellular spaces of the brain, has_symptom nausea, has_symptom vomiting, has_symptom blurred vision, has_symptom seizure, has_symptom coma. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Cerebral_edema "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aqp4 IEP 5148020RGDassociated with Drug-Induced Liver Injury;protein:increased expression:cerebral cortex 
Aqp4 IMP 5148010RGD  
Aqp4 ISOAqp4 (Rattus norvegicus)5148033RGDassociated with Anoxia 
Aqp4 ISOAqp4 (Rattus norvegicus)5490122RGDassociated with Drug-Induced Liver Injury;protein:increased expression:cerebral cortex, astrocyte, plasma membrane 
Aqp4 ISOAqp4 (Rattus norvegicus)5490126RGDassociated with Cerebral Hemorrhage 
Aqp4 ISOAqp4 (Rattus norvegicus)5490129RGDassociated with Embolism, Fat;protein:increased expression:brain 
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