GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Aqp4 | affects response to substance | EXP | | 6480464 | CTD | AQP4 protein affects the susceptibility to Ethanol | PMID:20615459 | Aqp4 | increases expression | EXP | | 6480464 | CTD | Ethanol results in increased expression of AQP4 mRNA | PMID:21955143 PMID:30319688 | Aqp4 | multiple interactions | EXP | | 6480464 | CTD | [AQP4 protein affects the susceptibility to Ethanol] which affects the abundance of Reactive Oxygen Species; [AQP4 protein affects the susceptibility to Ethanol] which affects the expression of CYP2E1 mRNA; [Ethanol co-treated with Galactose] results in decreased expression of AQP4 protein; [Ethanol co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of AQP4 protein; [ethylene dichloride co-treated with Ethanol] results in decreased expression of AQP4 mRNA; [ethylene dichloride co-treated with Ethanol] results in decreased expression of AQP4 protein; allyl sulfide inhibits the reaction [AQP4 protein affects the susceptibility to Ethanol] | PMID:20615459 PMID:30664321 PMID:33516661 | Aqp4 | increases expression | ISO | Aqp4 (Rattus norvegicus) | 6480464 | CTD | Ethanol results in increased expression of AQP4 protein | PMID:25029343 PMID:29339456 | Aqp4 | multiple interactions | ISO | Aqp4 (Rattus norvegicus) | 6480464 | CTD | Docosahexaenoic Acids inhibits the reaction [Ethanol results in increased expression of AQP4 protein] | PMID:25029343 | | ||||||||||||||||||||||
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