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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10173
Species: Mus musculus
RGD Object: Gene
Symbol: Apoa1
Name: apolipoprotein A-I
Acc ID: CHEBI:47775
Term: high-density lipoprotein cholesterol
Definition: Cholesterol esters and free cholesterol which are contained in or bound to high-density lipoproteins (HDL).
Chemical ID: MESH:D008076
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoa1increases abundanceEXP 6480464CTDAPOA1 protein results in increased abundance of Cholesterol, HDLPMID:20972769
Apoa1multiple interactionsEXP 6480464CTDAPOA1 protein inhibits the reaction [Lipopolysaccharides results in decreased abundance of Cholesterol, HDL]PMID:20972769
Apoa1affects bindingISOAPOA1 (Homo sapiens)6480464CTDPON1 protein binds to [APOA1 protein binds to Cholesterol, HDL]PMID:16128586
Apoa1increases abundanceISOApoa1 (Rattus norvegicus)6480464CTDAPOA1 protein results in increased abundance of Cholesterol, HDLPMID:18332268
Apoa1multiple interactionsISOAPOA1 (Homo sapiens)6480464CTDFatty Acids, Unsaturated affects the reaction [APOA1 promoter SNP affects the abundance of Cholesterol, HDL]PMID:11756058
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