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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10136
Species: Mus musculus
RGD Object: Gene
Symbol: Alb
Name: albumin
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Albaffects bindingISOALB (Homo sapiens)6480464CTDQuercetin metabolite binds to ALB proteinPMID:15884859
Albmultiple interactionsISOAlb (Rattus norvegicus)6480464CTD[Quercetin co-treated with Vitamin E] inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]; Quercetin inhibits the reaction [[Ranitidine co-treated with Diclofenac] results in decreased expression of ALB protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; Quercetin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Quercetin inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]PMID:17927767 PMID:20804811 PMID:28400101 PMID:34922902
Albmultiple interactionsISOALB (Homo sapiens)6480464CTDQuercetin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Quercetin promotes the reaction [2,2'-azobis(2-amidinopropane) results in increased degradation of ALB protein]PMID:11322927 PMID:23348005
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