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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10127
Species: Mus musculus
RGD Object: Gene
Symbol: Ahr
Name: aryl-hydrocarbon receptor
Acc ID: CHEBI:81582
Term: 2,4-dibromophenyl 2,4,5-tribromophenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, 5, 2', and 4' positions have been replaced by bromines.
Chemical ID: MESH:C477694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahrmultiple interactionsEXP 6480464CTD2,2',4,4',5-brominated diphenyl ether inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]PMID:16601081
Ahrmultiple interactionsISOAhr (Rattus norvegicus)6480464CTD2,2',4,4',5-brominated diphenyl ether binds to and results in increased activity of AHR protein; 2,2',4,4',5-brominated diphenyl ether inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]PMID:16601080 PMID:16601081
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