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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10127
Species: Mus musculus
RGD Object: Gene
Symbol: Ahr
Name: aryl-hydrocarbon receptor
Acc ID: CHEBI:81542
Term: Octachlorostyrene
Definition: An organochlorine compound that has formula C8Cl8.
Chemical ID: MESH:C014138
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahrmultiple interactionsEXP 6480464CTDAHR protein inhibits the reaction [octachlorostyrene results in increased activity of SULT1A1 protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased activity of UGT1A6A protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of CYP2B10 mRNA]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of NR1I3 protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of SULT1A1 mRNA]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of UGT1A6A mRNA]PMID:19525444
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