Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10127
Species: Mus musculus
RGD Object: Gene
Symbol: Ahr
Name: aryl-hydrocarbon receptor
Acc ID: CHEBI:3390
Term: carbaryl
Definition: A carbamate ester obtained by the formal condensation of 1-naphthol with methylcarbamic acid.
Chemical ID: MESH:D012721
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahrmultiple interactionsEXP 6480464CTDCarbaryl binds to and results in increased activity of AHR proteinPMID:9853009
Ahrmultiple interactionsISOAhr (Rattus norvegicus)6480464CTDCarbaryl binds to and results in increased activity of AHR proteinPMID:9853009
Ahrmultiple interactionsISOAHR (Homo sapiens)6480464CTDAHR protein affects the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]; Carbaryl binds to and results in increased activity of AHR protein; Carbaryl inhibits the reaction [beta-Naphthoflavone binds to and results in increased activity of AHR protein]PMID:17553063 PMID:9169082 PMID:9853009
Go Back to source page   Continue to Ontology report