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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10118
Species: Mus musculus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of AGT mRNAPMID:26377647
Agtdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of AGT mRNAPMID:23864506
Agtmultiple interactionsEXP 6480464CTDTetrachlorodibenzodioxin promotes the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]PMID:18670907
Agtdecreases expressionISOAgt (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AGT mRNAPMID:20959002 PMID:21215274 PMID:32109520
Agtdecreases expressionISOAGT (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AGT mRNAPMID:28011154
Agtmultiple interactionsISOAgt (Rattus norvegicus)6480464CTDAHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of AGT mRNA]PMID:21215274
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