GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | decreases abundance | EXP | | 6480464 | CTD | AGT protein results in decreased abundance of Nitric Oxide | PMID:17272743 | Agt | multiple interactions | EXP | | 6480464 | CTD | ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Nitric Oxide] | PMID:17272743 | Agt | decreases secretion | ISO | AGT (Homo sapiens) | 6480464 | CTD | AGT protein modified form results in decreased secretion of Nitric Oxide | PMID:17666345 | Agt | increases abundance | ISO | Agt (Rattus norvegicus) | 6480464 | CTD | AGT protein results in increased abundance of Nitric Oxide | PMID:14597853 | Agt | increases activity | ISO | Agt (Rattus norvegicus) | 6480464 | CTD | Nitric Oxide deficiency results in increased activity of AGT protein modified form | PMID:12198334 | Agt | increases chemical synthesis | ISO | AGT (Homo sapiens) | 6480464 | CTD | AGT protein modified form results in increased chemical synthesis of Nitric Oxide | PMID:29084084 | Agt | increases secretion | ISO | Agt (Rattus norvegicus) | 6480464 | CTD | AGT protein alternative form results in increased secretion of Nitric Oxide | PMID:18990443 | Agt | multiple interactions | ISO | Agt (Rattus norvegicus) | 6480464 | CTD | AGT protein alternative form promotes the reaction [NOS3 protein results in increased chemical synthesis of Nitric Oxide]; PD 123319 inhibits the reaction [AGT protein results in increased abundance of Nitric Oxide]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased abundance of Nitric Oxide]; Valsartan inhibits the reaction [AGT protein results in increased abundance of Nitric Oxide]; Valsartan inhibits the reaction [AGT protein results in increased secretion of Nitric Oxide] | PMID:14597853 PMID:14620932 PMID:18990443 PMID:35406003 | Agt | multiple interactions | ISO | AGT (Homo sapiens) | 6480464 | CTD | candesartan inhibits the reaction [AGT protein results in increased chemical synthesis of Nitric Oxide]; Hydrogen Sulfide promotes the reaction [AGT protein modified form results in increased chemical synthesis of Nitric Oxide]; Losartan inhibits the reaction [AGT protein modified form results in decreased secretion of Nitric Oxide]; troglitazone inhibits the reaction [AGT protein modified form results in decreased secretion of Nitric Oxide] | PMID:17666345 PMID:18551021 PMID:29084084 | | ||||||||||||||||||||||
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