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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10090
Species: Mus musculus
RGD Object: Gene
Symbol: Adh1
Name: alcohol dehydrogenase 1 (class I)
Acc ID: CHEBI:15343
Term: acetaldehyde
Definition: The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
Chemical ID: MESH:D000079
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adh1increases chemical synthesisEXP 6480464CTDADH1 protein results in increased chemical synthesis of AcetaldehydePMID:11893554
Adh1multiple interactionsEXP 6480464CTD[ADH1 protein co-treated with Ethanol] results in increased abundance of Acetaldehyde; [ADH1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde; Cyanamide promotes the reaction [[ADH1 protein co-treated with Ethanol] results in increased abundance of Acetaldehyde]; Cyanamide promotes the reaction [[ADH1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde]PMID:11981770 PMID:7646056
Adh1multiple interactionsISOADH1C (Homo sapiens)6480464CTD[ADH1C protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of AcetaldehydePMID:15138216
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