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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10064
Species: Mus musculus
RGD Object: Gene
Symbol: Acly
Name: ATP citrate lyase
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aclyincreases expressionEXP 6480464CTDPalmitic Acid results in increased expression of ACLY mRNAPMID:31421115
Aclymultiple interactionsEXP 6480464CTDacanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA]PMID:31421115
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