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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10057
Species: Mus musculus
RGD Object: Gene
Symbol: Acadm
Name: acyl-Coenzyme A dehydrogenase, medium chain
Acc ID: CHEBI:131843
Term: meldonium
Definition: An ammonium betaine that is beta-alaninate in which one of the amino hydrogens is replaced by a trimethylamino group. A clinically used cardioprotective drug that is used for treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes.
Chemical ID: MESH:C050147
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acadmdecreases expressionEXP 6480464CTD3-(2,2,2-trimethylhydrazine)propionate results in decreased expression of ACADM mRNAPMID:32389661
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