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GENE - TERM ANNOTATION REPORT

1 Annotations Found.

An association has been curated linking Insr and altered leptin system pathway in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
  •  
  • The annotation was made from Grillo CA, etal., Physiol Behav. 2007 Nov 23;92(4):691-701. Epub 2007 May 21.
  • 2 additional annotations were made from Grillo CA, etal., Physiol Behav. 2007 Nov 23;92(4):691-701. Epub 2007 May 21.
  • 4 RGD objects have been annotated to altered leptin system pathway  (PW:0000364)
  • 115 papers in RGD have been used to annotate Insr
  • Curation Notes: increased basal hypothalamic leptin signaling without changes in leptin receptor expression after antisense-mediated hypothalamus-specific Insr knock-down


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