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GENE - TERM ANNOTATION REPORT

1 Annotations Found.

An association has been curated linking Notch1 and altered Notch signaling pathway involving the main players in Chinchilla lanigera.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Automated assignment of GO, PW and RDO ISO annotations across species
  • The annotation has been inferred from sequence orthology with NOTCH1 (Homo sapiens)
  • 4 RGD objects have been annotated to altered Notch signaling pathway involving the main players  (PW:0000340)
  • 2 papers in RGD have been used to annotate Notch1
  • Curation Notes: Mutations in the dimerization and/or PEST domain have been associated with human acute T-lymphoblastic leukemias
  • Original References(s): PMID:15472075 REF_RGD_ID:1334450


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