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GENE - TERM ANNOTATION REPORT

8 Annotations Found.

An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from electronic annotation (IEA)
    		•  
  • The annotation was made from RGD automated data pipeline
  • The annotation has been inferred from electronic annotation with UniProtKB:P25098 & ensembl:ENSP00000312262
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2
  • Qualifier: involved_in
  • Curation Notes: GO_REF:0000107
  • Original References(s): GO_REF:0000107


    • An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Willets JM, etal., J Neurochem. 2007 Dec;103(6):2268-80. Epub 2007 Oct 1.
  • 2 additional annotations were made from Willets JM, etal., J Neurochem. 2007 Dec;103(6):2268-80. Epub 2007 Oct 1.
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2


    • An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Nash CA, etal., Cell Signal. 2018 Nov;51:86-98. doi: 10.1016/j.cellsig.2018.07.013. Epub 2018 Jul 31.
  • 3 additional annotations were made from Nash CA, etal., Cell Signal. 2018 Nov;51:86-98. doi: 10.1016/j.cellsig.2018.07.013. Epub 2018 Jul 31.
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2


    • An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD pipelines: Rat ISO annotations derived from the GO annotations of orthologous genes in other species.
  • The annotation has been inferred from sequence orthology with GRK2 (Homo sapiens)
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2
  • Qualifier: involved_in
  • Curation Notes: (PMID:15102938)
  • Original References(s): PMID:15102938


    • An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
    		•  
  • The annotation was made from Lymperopoulos A, etal., Mol Ther. 2008 Feb;16(2):302-7. doi: 10.1038/sj.mt.6300371. Epub 2007 Nov 27.
  • 1 additional annotations were made from Lymperopoulos A, etal., Mol Ther. 2008 Feb;16(2):302-7. doi: 10.1038/sj.mt.6300371. Epub 2007 Nov 27.
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2
  • Qualifier: involved_in
  • Curation Notes: PMID:18223549


    • An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from biological aspect of ancestor (IBA)
    		•  
  • The annotation was made from RGD automated data pipeline
  • The annotation has been inferred from biological aspect of ancestor with MGI:87940 & PANTHER:PTN008614780 & Grk2 (Rattus norvegicus) & Grk3 (Rattus norvegicus) & UniProtKB:P21146 & UniProtKB:P25098
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2
  • Qualifier: involved_in
  • Curation Notes: GO_REF:0000033
  • Original References(s): GO_REF:0000033


    • An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD pipelines: Rat ISO annotations derived from the GO annotations of orthologous genes in other species.
  • The annotation has been inferred from sequence orthology with Grk2 (Mus musculus)
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2
  • Qualifier: acts_upstream_of_or_within
  • Curation Notes: MGI:2180127|MGI:87937 (PMID:10338466), (PMID:7761854)
  • Original References(s): PMID:10338466 PMID:7761854


    • An association has been curated linking Grk2 and desensitization of G protein-coupled receptor signaling pathway in Rattus norvegicus.        

  • The association was inferred from electronic annotation (IEA)
    		•  
  • The annotation was made from RGD automated data pipeline
  • The annotation has been inferred from electronic annotation with UniProtKB:Q99MK8 & ensembl:ENSMUSP00000086114
  • 28 RGD objects have been annotated to desensitization of G protein-coupled receptor signaling pathway  (GO:0002029)
  • 93 papers in RGD have been used to annotate Grk2
  • Qualifier: acts_upstream_of_or_within
  • Curation Notes: GO_REF:0000107
  • Original References(s): GO_REF:0000107


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