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GENE - TERM ANNOTATION REPORT

9 Annotations Found.

An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Gutierrez-Aguilar R, etal., Obesity (Silver Spring). 2012 Feb;20(2):306-12. doi: 10.1038/oby.2011.236. Epub 2011 Jul 21.
  • 2 additional annotations were made from Gutierrez-Aguilar R, etal., Obesity (Silver Spring). 2012 Feb;20(2):306-12. doi: 10.1038/oby.2011.236. Epub 2011 Jul 21.
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r
  • Curation Notes: mRNA:decreased expression:hypothalamus (rat)


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Farooqi IS, etal., N Engl J Med. 2003 Mar 20;348(12):1085-95.
  • The annotation has been inferred from sequence orthology with MC4R (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 4 additional annotations were made from Farooqi IS, etal., N Engl J Med. 2003 Mar 20;348(12):1085-95.
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
  • The annotation has been inferred from sequence orthology with MC4R (Homo sapiens) [(IEA) inferred from electronic annotation]
  • 619 additional annotations were made from Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Stepp DW, etal., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13.
  • 66 additional annotations were made from Stepp DW, etal., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13.
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r
  • Curation Notes: DNA:nonsense mutation:cds:p.K314X (rat)


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Mul JD, etal., Obesity (Silver Spring). 2012 Mar;20(3):612-21. doi: 10.1038/oby.2011.81. Epub 2011 Apr 28.
  • 39 additional annotations were made from Mul JD, etal., Obesity (Silver Spring). 2012 Mar;20(3):612-21. doi: 10.1038/oby.2011.81. Epub 2011 Apr 28.
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r
  • Curation Notes: DNA:nonsense mutation:cds:p.K314X (rat)


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Huszar D, etal., Cell. 1997 Jan 10;88(1):131-41.
  • The annotation has been inferred from sequence orthology with Mc4r (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Huszar D, etal., Cell. 1997 Jan 10;88(1):131-41.
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with MC4R (Homo sapiens) [(EXP) inferred from experiment]
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:17143585 PMID:18454148 PMID:19079260 PMID:19079261 PMID:19151714 PMID:23251400


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with MC4R (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r
  • Curation Notes: ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, autosomal dominant
  • Original References(s): PMID:10078568 PMID:10199800 PMID:10577903 PMID:10592235 PMID:10903341 PMID:10903343 PMID:11443223 PMID:12364414 PMID:12364415 PMID:12499395 PMID:12588803 PMID:12629567 PMID:12646665 PMID:12646666 PMID:12690102 PMID:12815165 PMID:12851297 PMID:12959994 PMID:12970296 PMID:14633862 PMID:14764812 PMID:14764818 PMID:14973783 PMID:15037865 PMID:15126516 PMID:15448103 PMID:15466016 PMID:15486053 PMID:15585384 PMID:15805150 PMID:15975705 PMID:16030156 PMID:16032553 PMID:16083993 PMID:16094248 PMID:16231025 PMID:16274851 PMID:16289450 PMID:16469222 PMID:16492696 PMID:16507637 PMID:16611215 PMID:16614075 PMID:16616374 PMID:16710097 PMID:16752916 PMID:16960181 PMID:17185898 PMID:17286227 PMID:17306938 PMID:17357083 PMID:17492953 PMID:17517246 PMID:17519222 PMID:17579204 PMID:17590021 PMID:17628007 PMID:17668051 PMID:17986382 PMID:18559663 PMID:18801902 PMID:18997677 PMID:19011902 PMID:19091795 PMID:19179454 PMID:19184404 PMID:19244934 PMID:19284607 PMID:19298524 PMID:19301229 PMID:19400288 PMID:19417090 PMID:19766264 PMID:19889825 PMID:20462274 PMID:20631012 PMID:20696697 PMID:20826565 PMID:20966905 PMID:20975296 PMID:21085626 PMID:21404042 PMID:22106157 PMID:22447289 PMID:22463805 PMID:22688572 PMID:23146882 PMID:23251400 PMID:23505181 PMID:23791567 PMID:24276017 PMID:24385306 PMID:24512492 PMID:24611737 PMID:24705671 PMID:24780838 PMID:24890885 PMID:25076858 PMID:25136332 PMID:25332687 PMID:25741868 PMID:25741869 PMID:26047380 PMID:26179253 PMID:26238496 PMID:26244670 PMID:26467025 PMID:26588347 PMID:26666384 PMID:26782456 PMID:26788538 PMID:27222505 PMID:27654141 PMID:28166811 PMID:28492532 PMID:29273807 PMID:29311635 PMID:29758564 PMID:29861388 PMID:29970488 PMID:30048591 PMID:30811542 PMID:30926952 PMID:31002796 PMID:31118516 PMID:31841602 PMID:32534219 PMID:32952152 PMID:9267995


    • An association has been curated linking Mc4r and obesity in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with MC4R (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 784 RGD objects have been annotated to obesity  (DOID:9970)
  • 36 papers in RGD have been used to annotate Mc4r
  • Curation Notes: ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, autosomal dominant
  • Original References(s): PMID:10078568 PMID:10199800 PMID:10577903 PMID:10592235 PMID:10903341 PMID:10903343 PMID:11443223 PMID:12364414 PMID:12364415 PMID:12499395 PMID:12588803 PMID:12629567 PMID:12646665 PMID:12646666 PMID:12690102 PMID:12815165 PMID:12851297 PMID:12959994 PMID:12970296 PMID:14633862 PMID:14764812 PMID:14764818 PMID:14973783 PMID:15037865 PMID:15126516 PMID:15448103 PMID:15466016 PMID:15486053 PMID:15585384 PMID:15805150 PMID:15975705 PMID:16030156 PMID:16032553 PMID:16083993 PMID:16094248 PMID:16231025 PMID:16274851 PMID:16289450 PMID:16469222 PMID:16492696 PMID:16507637 PMID:16611215 PMID:16614075 PMID:16616374 PMID:16710097 PMID:16752916 PMID:16960181 PMID:17185898 PMID:17286227 PMID:17306938 PMID:17357083 PMID:17492953 PMID:17517246 PMID:17519222 PMID:17579204 PMID:17590021 PMID:17628007 PMID:17668051 PMID:17986382 PMID:18559663 PMID:18801902 PMID:18997677 PMID:19011902 PMID:19091795 PMID:19179454 PMID:19184404 PMID:19244934 PMID:19284607 PMID:19298524 PMID:19301229 PMID:19400288 PMID:19417090 PMID:19766264 PMID:19889825 PMID:20462274 PMID:20631012 PMID:20696697 PMID:20826565 PMID:20966905 PMID:20975296 PMID:21085626 PMID:21404042 PMID:22106157 PMID:22447289 PMID:22463805 PMID:22688572 PMID:23146882 PMID:23251400 PMID:23505181 PMID:23791567 PMID:24276017 PMID:24385306 PMID:24512492 PMID:24611737 PMID:24705671 PMID:24780838 PMID:24890885 PMID:25076858 PMID:25136332 PMID:25332687 PMID:25741868 PMID:25741869 PMID:26047380 PMID:26179253 PMID:26238496 PMID:26244670 PMID:26467025 PMID:26588347 PMID:26666384 PMID:26782456 PMID:26788538 PMID:27222505 PMID:27654141 PMID:28492532 PMID:29273807 PMID:29311635 PMID:29758564 PMID:29861388 PMID:29970488 PMID:30004997 PMID:30048591 PMID:30811542 PMID:30926952 PMID:31002796 PMID:31118516 PMID:31841602 PMID:32534219 PMID:32952152 PMID:9267995


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