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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking IL6 and obesity in Homo sapiens.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Sam S, etal., Diabetes Care. 2009 May;32(5):932-7. Epub 2009 Feb 19.
  • 2 additional annotations were made from Sam S, etal., Diabetes Care. 2009 May;32(5):932-7. Epub 2009 Feb 19.
  • 1153 RGD objects have been annotated to obesity  (DOID:9970)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)


    • An association has been curated linking IL6 and obesity in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Klipstein-Grobusch K, etal., Obesity (Silver Spring). 2006 Jan;14(1):14-8.
  • 2 additional annotations were made from Klipstein-Grobusch K, etal., Obesity (Silver Spring). 2006 Jan;14(1):14-8.
  • 1153 RGD objects have been annotated to obesity  (DOID:9970)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: DNA:polymorphism>promoter:174G>C


    • An association has been curated linking IL6 and obesity in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Chentouf M, etal., PLoS One. 2011;6(8):e22954. doi: 10.1371/journal.pone.0022954. Epub 2011 Aug 3.
  • The annotation has been inferred from sequence orthology with Il6 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Chentouf M, etal., PLoS One. 2011;6(8):e22954. doi: 10.1371/journal.pone.0022954. Epub 2011 Aug 3.
  • 1153 RGD objects have been annotated to obesity  (DOID:9970)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: mRNA:increased expression:islet of Langerhans


    • An association has been curated linking IL6 and obesity in Homo sapiens.        

  • The association was inferred from experiment (EXP)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • 1153 RGD objects have been annotated to obesity  (DOID:9970)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:20141834 PMID:24042701


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