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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking AKT1 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Chen WS, etal., Mol Cell Biol. 2009 Jun;29(11):3151-62. Epub 2009 Mar 16.
  • The annotation has been inferred from sequence orthology with Akt1 (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 8 additional annotations were made from Chen WS, etal., Mol Cell Biol. 2009 Jun;29(11):3151-62. Epub 2009 Mar 16.
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 92 papers in RGD have been used to annotate AKT1


    • An association has been curated linking AKT1 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Lee JH, etal., Am J Physiol Cell Physiol. 2009 Feb;296(2):C327-38. Epub 2008 Dec 3.
  • The annotation has been inferred from sequence orthology with Akt1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Lee JH, etal., Am J Physiol Cell Physiol. 2009 Feb;296(2):C327-38. Epub 2008 Dec 3.
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 92 papers in RGD have been used to annotate AKT1
  • Curation Notes: protein:increased serine phosphorylation:vascular associated smooth muscle cell


    • An association has been curated linking AKT1 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred from experiment (EXP)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 92 papers in RGD have been used to annotate AKT1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:31626838


    • An association has been curated linking AKT1 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zhang Q, etal., J Integr Med. 2014 May;12(3):162-70. doi: 10.1016/S2095-4964(14)60020-0.
  • The annotation has been inferred from sequence orthology with Akt1 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Zhang Q, etal., J Integr Med. 2014 May;12(3):162-70. doi: 10.1016/S2095-4964(14)60020-0.
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 92 papers in RGD have been used to annotate AKT1
  • Qualifier: treatment


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