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GENE - TERM ANNOTATION REPORT

7 Annotations Found.

An association has been curated linking IL6 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Koh SJ, etal., Clin Endocrinol (Oxf). 2009 Feb;70(2):238-44. Epub 2008 Jun 20.
  • 2 additional annotations were made from Koh SJ, etal., Clin Endocrinol (Oxf). 2009 Feb;70(2):238-44. Epub 2008 Jun 20.
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: DNA:polymorphism:promoter:-572C>G (human)


    • An association has been curated linking IL6 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Barbu A, etal., Mol Cell Endocrinol. 2009 Feb 27;299(2):163-71. Epub 2008 Nov 25.
  • The annotation has been inferred from sequence orthology with Il6 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Barbu A, etal., Mol Cell Endocrinol. 2009 Feb 27;299(2):163-71. Epub 2008 Nov 25.
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: mRNA:increased expression:adipose tissue


    • An association has been curated linking IL6 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Stringer DM, etal., Pediatr Diabetes. 2008 Oct 15.
  • 2 additional annotations were made from Stringer DM, etal., Pediatr Diabetes. 2008 Oct 15.
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: protein:increased expression:extracellular space (human)


    • An association has been curated linking IL6 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Nadeem A, etal., J Pak Med Assoc. 2017 Mar;67(3):428-433.
  • 2 additional annotations were made from Nadeem A, etal., J Pak Med Assoc. 2017 Mar;67(3):428-433.
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: DNA, protein:SNP, increased expression:promoter:serum, -174G>C (human)


    • An association has been curated linking IL6 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred from experiment (EXP)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: CTD Direct Evidence: marker/mechanism


    • An association has been curated linking IL6 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from OMIM Disease Annotation Pipeline
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 337 papers in RGD have been used to annotate IL6


    • An association has been curated linking IL6 and type 2 diabetes mellitus in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred by association of genotype and phenotype with RGD:8564423 (Homo sapiens)
  • 1031 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 337 papers in RGD have been used to annotate IL6
  • Curation Notes: ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
  • Original References(s): PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 PMID:12560873 PMID:12719374 PMID:15070960 PMID:15331795 PMID:15472205 PMID:16150725 PMID:16278864 PMID:17623760 PMID:18550579 PMID:9769329


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