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GENE - TERM ANNOTATION REPORT

8 Annotations Found.

An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Murugan P, etal., J Biosci. 2008 Mar;33(1):63-72.
  • The annotation has been inferred from sequence orthology with Insr (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Murugan P, etal., J Biosci. 2008 Mar;33(1):63-72.
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Curation Notes: protein:decreased expression:erythrocyte (rat)


    • An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Ekladous D, etal., Clin Exp Pharmacol Physiol. 2008 Aug;35(8):971-8. Epub 2008 Apr 21.
  • The annotation has been inferred from sequence orthology with Insr (Rattus norvegicus)
  • 4 additional annotations were made from Ekladous D, etal., Clin Exp Pharmacol Physiol. 2008 Aug;35(8):971-8. Epub 2008 Apr 21.
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Curation Notes: protein:increased expression:gastrocnemius (rat)


    • An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Calle C, etal., BMC Mol Biol. 2008 Jul 18;9:65.
  • The annotation has been inferred from sequence orthology with Insr (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 3 additional annotations were made from Calle C, etal., BMC Mol Biol. 2008 Jul 18;9:65.
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Curation Notes: mRNA, protein:increased expression:liver, adipose tissue (rat)


    • An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Tiwari S, etal., J Am Soc Nephrol. 2007 Oct;18(10):2661-71. Epub 2007 Sep 12.
  • The annotation has been inferred from sequence orthology with Insr (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Tiwari S, etal., J Am Soc Nephrol. 2007 Oct;18(10):2661-71. Epub 2007 Sep 12.
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Curation Notes: protein:decreased expression:kidney


    • An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Blondel O, etal., Am J Physiol. 1990 Mar;258(3 Pt 1):E459-67. doi: 10.1152/ajpendo.1990.258.3.E459.
  • The annotation has been inferred from sequence orthology with Insr (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 6 additional annotations were made from Blondel O, etal., Am J Physiol. 1990 Mar;258(3 Pt 1):E459-67. doi: 10.1152/ajpendo.1990.258.3.E459.
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Curation Notes: associated with streptozocin;protein:altered activity:liver plasma membrane (rat)


    • An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from experiment (EXP)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:9243097 PMID:22138235


    • An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Tozzo E and Desbuquois B, Diabetes. 1992 Dec;41(12):1609-16. doi: 10.2337/diab.41.12.1609.
  • The annotation has been inferred from sequence orthology with Insr (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 10 additional annotations were made from Tozzo E and Desbuquois B, Diabetes. 1992 Dec;41(12):1609-16. doi: 10.2337/diab.41.12.1609.
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Qualifier: disease_progression
  • Curation Notes: mRNA:increased expression:liver nuclei, liver cell membrane (rat)


    • An association has been curated linking INSR and Experimental Diabetes Mellitus in Homo sapiens.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Kim MH, etal., PLoS One. 2013 Jul 9;8(7):e67802. doi: 10.1371/journal.pone.0067802. Print 2013.
  • 2 additional annotations were made from Kim MH, etal., PLoS One. 2013 Jul 9;8(7):e67802. doi: 10.1371/journal.pone.0067802. Print 2013.
  • 585 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 67 papers in RGD have been used to annotate INSR
  • Qualifier: treatment


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