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GENE - TERM ANNOTATION REPORT

2 Annotations Found.

An association has been curated linking Ace2 and pulmonary hypertension in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with ACE2 (Homo sapiens) [(EXP) inferred from experiment]
  • 414 RGD objects have been annotated to pulmonary hypertension  (DOID:6432)
  • 73 papers in RGD have been used to annotate Ace2
  • Curation Notes: CTD Direct Evidence: therapeutic
  • Original References(s): PMID:31931441


    • An association has been curated linking Ace2 and pulmonary hypertension in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Shenoy V, etal., Hypertension. 2014 Dec;64(6):1248-59. doi: 10.1161/HYPERTENSIONAHA.114.03871. Epub 2014 Sep 15.
  • The annotation has been inferred from sequence orthology with ACE2 (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Shenoy V, etal., Hypertension. 2014 Dec;64(6):1248-59. doi: 10.1161/HYPERTENSIONAHA.114.03871. Epub 2014 Sep 15.
  • 414 RGD objects have been annotated to pulmonary hypertension  (DOID:6432)
  • 73 papers in RGD have been used to annotate Ace2
  • Qualifier: treatment
  • Curation Notes: human protein in a rat model


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