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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking Zic2 and holoprosencephaly in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Ribeiro LA, etal., Birth Defects Res A Clin Mol Teratol. 2012 Nov;94(11):912-7. doi: 10.1002/bdra.23047. Epub 2012 Jul 27.
  • The annotation has been inferred from sequence orthology with ZIC2 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Ribeiro LA, etal., Birth Defects Res A Clin Mol Teratol. 2012 Nov;94(11):912-7. doi: 10.1002/bdra.23047. Epub 2012 Jul 27.
  • 214 RGD objects have been annotated to holoprosencephaly  (DOID:4621)
  • 16 papers in RGD have been used to annotate Zic2
  • Curation Notes: DNA:deletion, duplication, frameshift, transition mutations:cds,intron:


  • An association has been curated linking Zic2 and holoprosencephaly in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Brown SA, etal., Nat Genet. 1998 Oct;20(2):180-3.
  • The annotation has been inferred from sequence orthology with ZIC2 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Brown SA, etal., Nat Genet. 1998 Oct;20(2):180-3.
  • 214 RGD objects have been annotated to holoprosencephaly  (DOID:4621)
  • 16 papers in RGD have been used to annotate Zic2
  • Curation Notes: DNA:insertion,deletion mutations:cds:


  • An association has been curated linking Zic2 and holoprosencephaly in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Warr N, etal., Hum Mol Genet. 2008 Oct 1;17(19):2986-96. doi: 10.1093/hmg/ddn197. Epub 2008 Jul 9.
  • The annotation has been inferred from sequence orthology with Zic2 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Warr N, etal., Hum Mol Genet. 2008 Oct 1;17(19):2986-96. doi: 10.1093/hmg/ddn197. Epub 2008 Jul 9.
  • 214 RGD objects have been annotated to holoprosencephaly  (DOID:4621)
  • 16 papers in RGD have been used to annotate Zic2


  • An association has been curated linking Zic2 and holoprosencephaly in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with ZIC2 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 214 RGD objects have been annotated to holoprosencephaly  (DOID:4621)
  • 16 papers in RGD have been used to annotate Zic2
  • Curation Notes: ClinVar Annotator: match by term: Holoprosencephaly sequence | ClinVar Annotator: match by term: Lobar holoprosencephaly
  • Original References(s): PMID:25741868


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