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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking Tlr4 and macular degeneration in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Cho Y, etal., Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5614-8. doi: 10.1167/iovs.09-3688. Epub 2009 Jul 23.
  • The annotation has been inferred from sequence orthology with TLR4 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Cho Y, etal., Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5614-8. doi: 10.1167/iovs.09-3688. Epub 2009 Jul 23.
  • 156 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 247 papers in RGD have been used to annotate Tlr4
  • Qualifier: no_association
  • Curation Notes: DNA:SNP:: rs4986790(human)


    • An association has been curated linking Tlr4 and macular degeneration in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zareparsi S, etal., Hum Mol Genet. 2005 Jun 1;14(11):1449-55. Epub 2005 Apr 13.
  • The annotation has been inferred from sequence orthology with TLR4 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Zareparsi S, etal., Hum Mol Genet. 2005 Jun 1;14(11):1449-55. Epub 2005 Apr 13.
  • 156 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 247 papers in RGD have been used to annotate Tlr4
  • Qualifier: susceptibility
  • Curation Notes: DNA:polymorphism:exon:p.D299G(human)


    • An association has been curated linking Tlr4 and macular degeneration in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Despriet DD, etal., Invest Ophthalmol Vis Sci. 2008 Jan;49(1):364-71. doi: 10.1167/iovs.07-0656.
  • The annotation has been inferred from sequence orthology with TLR4 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 5 additional annotations were made from Despriet DD, etal., Invest Ophthalmol Vis Sci. 2008 Jan;49(1):364-71. doi: 10.1167/iovs.07-0656.
  • 156 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 247 papers in RGD have been used to annotate Tlr4
  • Qualifier: no_association
  • Curation Notes: DNA:SNPs: :p.D299G,T399I(human)


    • An association has been curated linking Tlr4 and macular degeneration in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with TLR4 (Homo sapiens) [(EXP) inferred from experiment]
  • 156 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 247 papers in RGD have been used to annotate Tlr4
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:15829498


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