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GENE - TERM ANNOTATION REPORT

7 Annotations Found.

An association has been curated linking TGFB1 and pulmonary fibrosis in Homo sapiens.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Pulichino AM, etal., Am J Respir Cell Mol Biol. 2008 Sep;39(3):324-36. Epub 2008 Apr 10.
  • 2 additional annotations were made from Pulichino AM, etal., Am J Respir Cell Mol Biol. 2008 Sep;39(3):324-36. Epub 2008 Apr 10.
  • 275 RGD objects have been annotated to pulmonary fibrosis  (DOID:3770)
  • 222 papers in RGD have been used to annotate TGFB1


    • An association has been curated linking TGFB1 and pulmonary fibrosis in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Mabalirajan U, etal., Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L411-9. Epub 2009 Jun 19.
  • The annotation has been inferred from sequence orthology with Tgfb1 (Mus musculus) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Mabalirajan U, etal., Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L411-9. Epub 2009 Jun 19.
  • 275 RGD objects have been annotated to pulmonary fibrosis  (DOID:3770)
  • 222 papers in RGD have been used to annotate TGFB1
  • Curation Notes: associated with Asthma


    • An association has been curated linking TGFB1 and pulmonary fibrosis in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Russo RC, etal., Am J Respir Cell Mol Biol. 2010 Sep 10.
  • The annotation has been inferred from sequence orthology with Tgfb1 (Mus musculus) [(IEP) inferred from expression pattern]
  • 8 additional annotations were made from Russo RC, etal., Am J Respir Cell Mol Biol. 2010 Sep 10.
  • 275 RGD objects have been annotated to pulmonary fibrosis  (DOID:3770)
  • 222 papers in RGD have been used to annotate TGFB1
  • Curation Notes: protein:increased expression:lung


    • An association has been curated linking TGFB1 and pulmonary fibrosis in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Wang X, etal., Respir Res. 2009 May 13;10(1):36.
  • The annotation has been inferred from sequence orthology with Tgfb1 (Rattus norvegicus) [(IMP) inferred from mutant phenotype]
  • 5 additional annotations were made from Wang X, etal., Respir Res. 2009 May 13;10(1):36.
  • 275 RGD objects have been annotated to pulmonary fibrosis  (DOID:3770)
  • 222 papers in RGD have been used to annotate TGFB1
  • Curation Notes: associated with Silicosis


    • An association has been curated linking TGFB1 and pulmonary fibrosis in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Hao Y and Liu Y, Biol Pharm Bull. 2016;39(4):457-65. doi: 10.1248/bpb.b15-00358. Epub 2016 Jan 28.
  • The annotation has been inferred from sequence orthology with Tgfb1 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Hao Y and Liu Y, Biol Pharm Bull. 2016;39(4):457-65. doi: 10.1248/bpb.b15-00358. Epub 2016 Jan 28.
  • 275 RGD objects have been annotated to pulmonary fibrosis  (DOID:3770)
  • 222 papers in RGD have been used to annotate TGFB1
  • Qualifier: treatment


    • An association has been curated linking TGFB1 and pulmonary fibrosis in Homo sapiens.        

  • The association was inferred from experiment (EXP)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • 275 RGD objects have been annotated to pulmonary fibrosis  (DOID:3770)
  • 222 papers in RGD have been used to annotate TGFB1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:15286001 PMID:16324872 PMID:16365456 PMID:17266442 PMID:19817698 PMID:24762191 PMID:26817844


    • An association has been curated linking TGFB1 and pulmonary fibrosis in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Kim J, etal., J Microbiol Biotechnol. 2020 Mar 28;30(3):427-438. doi: 10.4014/jmb.1910.10055.
  • The annotation has been inferred from sequence orthology with Tgfb1 (Mus musculus) [(IEP) inferred from expression pattern]
  • 23 additional annotations were made from Kim J, etal., J Microbiol Biotechnol. 2020 Mar 28;30(3):427-438. doi: 10.4014/jmb.1910.10055.
  • 275 RGD objects have been annotated to pulmonary fibrosis  (DOID:3770)
  • 222 papers in RGD have been used to annotate TGFB1
  • Curation Notes: associated with Middle East respiratory syndrome;mRNA:increased expression:lung


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