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GENE - TERM ANNOTATION REPORT

2 Annotations Found.

An association has been curated linking IGF1 and Noonan syndrome in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from De Rocca Serra-Nedelec A, etal., Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4257-62. doi: 10.1073/pnas.1119803109. Epub 2012 Feb 27.
  • The annotation has been inferred from sequence orthology with Igf1 (Mus musculus) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from De Rocca Serra-Nedelec A, etal., Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4257-62. doi: 10.1073/pnas.1119803109. Epub 2012 Feb 27.
  • 71 RGD objects have been annotated to Noonan syndrome  (DOID:3490)
  • 167 papers in RGD have been used to annotate IGF1
  • Curation Notes: protein:decreased expression:serum (mouse)


    • An association has been curated linking IGF1 and Noonan syndrome in Homo sapiens.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Limal JM, etal., J Clin Endocrinol Metab. 2006 Jan;91(1):300-6. Epub 2005 Nov 1.
  • 5 additional annotations were made from Limal JM, etal., J Clin Endocrinol Metab. 2006 Jan;91(1):300-6. Epub 2005 Nov 1.
  • 71 RGD objects have been annotated to Noonan syndrome  (DOID:3490)
  • 167 papers in RGD have been used to annotate IGF1
  • Qualifier: treatment


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