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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking Nr1h4 and extrahepatic cholestasis in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
    		•  
  • The annotation was made from Liu Y, etal., J Clin Invest. 2003 Dec;112(11):1678-87. Epub 2003 Nov 17.
  • 2 additional annotations were made from Liu Y, etal., J Clin Invest. 2003 Dec;112(11):1678-87. Epub 2003 Nov 17.
  • 51 RGD objects have been annotated to extrahepatic cholestasis  (DOID:13619)
  • 70 papers in RGD have been used to annotate Nr1h4


    • An association has been curated linking Nr1h4 and extrahepatic cholestasis in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Modica S, etal., Gastroenterology. 2012 Feb;142(2):355-65.e1-4. doi: 10.1053/j.gastro.2011.10.028. Epub 2011 Nov 2.
  • The annotation has been inferred from sequence orthology with NR1H4 (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Modica S, etal., Gastroenterology. 2012 Feb;142(2):355-65.e1-4. doi: 10.1053/j.gastro.2011.10.028. Epub 2011 Nov 2.
  • 51 RGD objects have been annotated to extrahepatic cholestasis  (DOID:13619)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Curation Notes: human gene in mouse model


    • An association has been curated linking Nr1h4 and extrahepatic cholestasis in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Jia WJ, etal., Mol Med Rep. 2018 Jan;17(1):1545-1554. doi: 10.3892/mmr.2017.8025. Epub 2017 Nov 10.
  • 6 additional annotations were made from Jia WJ, etal., Mol Med Rep. 2018 Jan;17(1):1545-1554. doi: 10.3892/mmr.2017.8025. Epub 2017 Nov 10.
  • 51 RGD objects have been annotated to extrahepatic cholestasis  (DOID:13619)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Qualifier: disease_progression
  • Curation Notes: protein:increased expression:liver (rat)


    • An association has been curated linking Nr1h4 and extrahepatic cholestasis in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Zhu L, etal., J Hepatobiliary Pancreat Sci. 2018 Mar;25(3):195-205. doi: 10.1002/jhbp.537.
  • 14 additional annotations were made from Zhu L, etal., J Hepatobiliary Pancreat Sci. 2018 Mar;25(3):195-205. doi: 10.1002/jhbp.537.
  • 51 RGD objects have been annotated to extrahepatic cholestasis  (DOID:13619)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Qualifier: treatment
  • Curation Notes: mRNA:increased expression:liver (rat)


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